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Identification of therapeutic targets from genetic association studies using hierarchical component analysis
Abstract Background Mapping disease-associated genetic variants to complex disease pathophysiology is a major challenge in translating findings from genome-wide association studies into novel therapeutic opportunities. The difficulty lies in our limited understanding of how phenotypic traits arise f...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-06-01
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| Colecção: | BioData Mining |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13040-020-00216-9 |
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