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Incidence and Prognostic Impact of DNMT3A Mutations in Korean Normal Karyotype Acute Myeloid Leukemia Patients

Background. DNA methyltransferase 3A (DNMT3A) mutation was recently introduced as a prognostic indicator in normal karyotype (NK) AML and we evaluated the incidence and prognostic impact of DNMT3A mutations in Korean NK AML patients. Methods. Total 67 NK AML patients diagnosed during the recent 10 y...

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Detalhes bibliográficos
Main Authors: Sang Hyuk Park, Jae-Cheol Choi, Shine Young Kim, Jongyoun Yi, Seung Hwan Oh, In-Suk Kim, Hyung-Hoi Kim, Chulhun Ludgerus Chang, Eun Yup Lee, Moo-Kon Song, Ho-Jin Shin, Joo Seop Chung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2015-01-01
Colecção:BioMed Research International
Acesso em linha:http://dx.doi.org/10.1155/2015/723682
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