Assessment of radial glia in the frontal lobe of fetuses with Down syndrome

Abstract Down syndrome (DS) occurs with triplication of human chromosome 21 and is associated with deviations in cortical development evidenced by simplified gyral appearance and reduced cortical surface area. Radial glia are neuronal and glial progenitors that also create a scaffolding structure es...

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Hlavní autoři: Ana A. Baburamani, Regina T. Vontell, Alena Uus, Maximilian Pietsch, Prachi A. Patkee, Jo Wyatt-Ashmead, Evonne C. Chin-Smith, Veena G. Supramaniam, J. Donald Tournier, Maria Deprez, Mary A. Rutherford
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2020-08-01
Edice:Acta Neuropathologica Communications
Témata:
Cortical development
Radial glia
Fetal brain
Down syndrome
SOX2
Diffusion MRI
On-line přístup:http://link.springer.com/article/10.1186/s40478-020-01015-3
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