The regulatory role of NAAG-mGluR3 signaling on cortical synaptic plasticity after hypoxic ischemia

Abstract Background Synapses can adapt to changes in the intracerebral microenvironment by regulation of presynaptic neurotransmitter release and postsynaptic neurotransmitter receptor expression following hypoxic ischemia (HI) injury. The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) ex...

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Main Authors: Kexin Li, Meng Lu, Mengxu Cui, Xiaoming Wang, Yang Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Cell Communication and Signaling
Assuntos:
Hypoxic-ischemic injury
N-acetylaspartylglutamate
Metabotropic glutamate receptor
Synaptic plasticity
Acesso em linha:https://doi.org/10.1186/s12964-022-00866-8
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