Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer

Abstract Background Prostate cancer (PCa) is a heterogeneous disease with a variable natural history, genetics, and treatment outcome. The Hedgehog (Hh) signaling pathway is increasingly recognized as being potentially important for the development and progression of PCa. In this retrospective study...

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Autori principali: Annelies Gonnissen, Sofie Isebaert, Christiaan Perneel, Chad M. McKee, Clare Verrill, Richard J. Bryant, Filip Van Utterbeeck, Evelyne Lerut, Karin Haustermans, Ruth J. Muschel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2017-09-01
Serie:BMC Cancer
Soggetti:
Hedgehog pathway
Prostate cancer
Tissue microarray
Biochemical recurrence
Accesso online:http://link.springer.com/article/10.1186/s12885-017-3619-4
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