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Proteomic Profiling of the Dystrophin-Deficient mdx Phenocopy of Dystrophinopathy-Associated Cardiomyopathy

Cardiorespiratory complications are frequent symptoms of Duchenne muscular dystrophy, a neuromuscular disorder caused by primary abnormalities in the dystrophin gene. Loss of cardiac dystrophin initially leads to changes in dystrophin-associated glycoproteins and subsequently triggers secondarily sa...

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Autori principali: Ashling Holland, Kay Ohlendieck
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Limited 2014-01-01
Serie:BioMed Research International
Accesso online:http://dx.doi.org/10.1155/2014/246195
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