Noncanonical PD-1/PD-L1 Axis in Relation to the Efficacy of Anti-PD Therapy

With programmed death 1/ligand 1 (PD-1/PD-L1) as the cornerstone, anti-PD antibodies have pioneered revolutionary immunotherapies for malignancies. But most patients struggled to respond to anti-PD owing to primary or acquired resistance or even hyperprogression, pointing to more efforts needed to e...

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Bibliografski detalji
Glavni autori: Yiru Long, Xiaolu Yu, Runqiu Chen, Yongliang Tong, Likun Gong
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-05-01
Serija:Frontiers in Immunology
Teme:
noncanonical PD-1/PD-L1 axis
T-cells
tumor cells
myeloid cells
anti-PD therapy
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.910704/full
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