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Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening

Butyrylcholinesterase (BChE) plays an important role in the progression of the Alzheimer’s disease. In this study, we used a structure-based virtual screening (VS) approach to discover new BChE inhibitors. A ligand database was filtered and docked to the BChE protein using Glide program. The outcome...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Noor Atatreh, Sara Al Rawashdah, Shaikha S. Al Neyadi, Sawsan M. Abuhamdah, Mohammad A. Ghattas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis Group 2019-01-01
श्रृंखला:Journal of Enzyme Inhibition and Medicinal Chemistry
विषय:
ऑनलाइन पहुंच:http://dx.doi.org/10.1080/14756366.2019.1644329
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