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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis

Surgery-induced microglial activation is critical in mediating postoperative cognitive dysfunction (POCD) in elderly patients, where the important protective effect of dexmedetomidine has been indicated. However, the mechanisms of action of dexmedetomidine during the neuroinflammatory response that...

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Hlavní autoři: Zhichao Wu, Han Wang, Zuan Shi, Yalan Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Limited 2022-01-01
Edice:Neural Plasticity
On-line přístup:http://dx.doi.org/10.1155/2022/1353778
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