Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy

Abstract Background Estrogen receptor β (ERβ) has been reported to play an anti-cancer role in breast cancer, but the regulatory mechanism by which ERβ exerts this effect is not clear. Claudin-6 (CLDN6), a tight junction protein, acts as a tumor suppressor gene in breast cancer. Our previous studies...

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Main Authors: Peiye Song, Yanru Li, Yuan Dong, Yingying Liang, Huinan Qu, Da Qi, Yan Lu, Xiangshu Jin, Yantong Guo, Yiyang Jia, Xinqi Wang, Wenhong Xu, Chengshi Quan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-08-01
Colecção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Estrogen receptor β
CLDN6
Autophagy
Migration
Invasion
Breast cancer
Acesso em linha:http://link.springer.com/article/10.1186/s13046-019-1359-9
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