Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.

Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous functions in liver, both in health and disease. Here we report that TLR3 is expressed by quiescent hepatic stellate cells (HSC) where it functions to induce t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Caroline L Wilson, Jelena Mann, Meagan Walsh, Maria J Perrugoria, Fiona Oakley, Matthew C Wright, Chiara Brignole, Daniela Di Paolo, Patrizia Perri, Mirco Ponzoni, Michael Karin, Derek A Mann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3885413?pdf=render
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados