Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS

Background The enterosalivary nitrate–nitrite–nitric oxide (NO3–NO2–NO) pathway generates NO following oral microbiota‐mediated production of salivary nitrite, potentially linking the oral microbiota to reduced cardiometabolic risk. Nitrite depletion by oral bacteria may also be important for determ...

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Detalhes bibliográficos
Main Authors: Charlene E. Goh, Bruno Bohn, Clarisse Marotz, Rebecca Molinsky, Sumith Roy, Bruce J. Paster, Ching‐Yuan Chen, Michael Rosenbaum, Melana Yuzefpolskaya, Paolo C. Colombo, Moïse Desvarieux, Panos N. Papapanou, David R. Jacobs, Rob Knight, Ryan T. Demmer
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-05-01
Colecção:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:
16S rNA sequencing
blood pressure
epidemiology
insulin resistance
metagenomics
nitric oxide
Acesso em linha:https://www.ahajournals.org/doi/10.1161/JAHA.121.023038
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