Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke

Insulin-like growth factor 1 (Igf1) and insulin-like growth factor binding protein 3 (Igfbp3) are endocrine and paracrine factors that influence stroke occurrence, severity, and recovery. Low levels of endocrine Igf1 and Igfbp3 were associated with larger infarct volumes and unfavorable outcomes. Pa...

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Main Authors: Christian J. Hoffmann, Melanie T. C. Kuffner, Janet Lips, Stephanie Lorenz, Matthias Endres, Christoph Harms
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Physiology
Assuntos:
ZFP580
IGF1
IGFBP3
stroke
paracrine
endocrine
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphys.2022.887180/full
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