Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus

While most broadly neutralizing antibodies (bnAb) against Influenza virus target conserved conformational epitopes of the glycoprotein hemagglutinin (HA), Sun et al. characterize a lineage of bnAbs that neutralize group 1 and 2 strains. Structural characterization shows that antibody 28-12 binds a c...

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Detalhes bibliográficos
Main Authors: Xiaoyu Sun, Caixuan Liu, Xiao Lu, Zhiyang Ling, Chunyan Yi, Zhen Zhang, Zi Li, Mingliang Jin, Wenshuai Wang, Shubing Tang, Fangfang Wang, Fang Wang, Sonam Wangmo, Shuangfeng Chen, Li Li, Liyan Ma, Yaguang Zhang, Zhuo Yang, Xiaoping Dong, Zhikang Qian, Jianping Ding, Dayan Wang, Yao Cong, Bing Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-05-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-022-29950-w
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