Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering

Abstract Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the expansion of mesenchymal stromal cells (MSCs) for bone tissue engineering (BTE) applications. Due to a growing demand, the need for standardization and scaling-up of HPL has been highlighted. Ho...

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Main Authors: Siddharth Shanbhag, Samih Mohamed-Ahmed, Turid Helen Felli Lunde, Salwa Suliman, Anne Isine Bolstad, Tor Hervig, Kamal Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-09-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Platelet lysate
Mesenchymal stromal cells
Bone tissue engineering
Regenerative medicine
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01863-9
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