Zinc oxide nanoparticles inhibit osteosarcoma metastasis by downregulating β-catenin via HIF-1α/BNIP3/LC3B-mediated mitophagy pathway

Osteosarcoma (OS) therapy faces many challenges, especially the poor survival rate once metastasis occurs. Therefore, it is crucial to explore new OS treatment strategies that can efficiently inhibit OS metastasis. Bioactive nanoparticles such as zinc oxide nanoparticles (ZnO NPs) can efficiently in...

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Detalhes bibliográficos
Main Authors: Guanping He, Jing-Jun Nie, Xiao Liu, Zihao Ding, Peng Luo, Yu Liu, Bo-Wen Zhang, Renxian Wang, Xiaoguang Liu, Yong Hai, Da-Fu Chen
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2023-01-01
Colecção:Bioactive Materials
Assuntos:
Zinc oxide nanoparticle
HIF-1α/BNIP3/LC3B-mediated mitophagy pathway
Metastasis
Osteosarcoma
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452199X22002171
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