Autophagy, TGF-beta and SMAD-2/3 signaling regulates interferon-beta response in respiratory syncytial virus infected macrophages

Human respiratory syncytial virus (RSV) is a lung tropic virus causing severe airway diseases including bronchiolitis and pneumonia among infants, children and immuno-compromised individuals. RSV triggers transforming growth factor-beta(TGF-beta) production from lung epithelial cells and TGF-beta...

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Main Authors: Swechha Pokharel, Niraj Shil, Santanu Bose
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016-12-01
Serija:Frontiers in Cellular and Infection Microbiology
Teme:
Autophagy
Interferon-beta
Macrophages
TGF-beta
Smad
respiratory syncytial virus
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00174/full
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