Genome amplification and cellular senescence are hallmarks of human placenta development.

Genome amplification and cellular senescence are commonly associated with pathological processes. While physiological roles for polyploidization and senescence have been described in mouse development, controversy exists over their significance in humans. Here, we describe tetraploidization and sene...

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Detalhes bibliográficos
Main Authors: Philipp Velicky, Gudrun Meinhardt, Kerstin Plessl, Sigrid Vondra, Tamara Weiss, Peter Haslinger, Thomas Lendl, Karin Aumayr, Mario Mairhofer, Xiaowei Zhu, Birgit Schütz, Roberta L Hannibal, Robert Lindau, Beatrix Weil, Jan Ernerudh, Jürgen Neesen, Gerda Egger, Mario Mikula, Clemens Röhrl, Alexander E Urban, Julie Baker, Martin Knöfler, Jürgen Pollheimer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-10-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC6200260?pdf=render
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