Beyond Gap Junction Channel Function: the Expression of Cx43 Contributes to Aldosterone-Induced Mesangial Cell Proliferation via the ERK1/2 and PKC Pathways

Aims: This study aimed to explore the precise mechanism and signaling pathways of mesangial cell (MC) proliferation from a new point of view considering Connexin 43 (Cx43). Methods: MC proliferation was measured by the incorporation of 3H-thymidine (3H-TdR). Cx43 was over-expressed in MC cells using...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aiqing Zhang, Ying Han, Bin Wang, Shanwen Li, Weihua Gan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Physiol Biochem Press GmbH & Co KG 2015-06-01
Saila:Cellular Physiology and Biochemistry
Gaiak:
Connexin 43
Gap junction
Mesangial cells
Proliferation
Sarrera elektronikoa:http://www.karger.com/Article/FullText/430291
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