ADAR1 promotes HBV replication through its deaminase domain

Adenosine deaminase acting on RNA1 (ADAR1) is an RNA editing enzyme that modulates the replication of several viruses. Here, we provide evidence showing that ADAR1 stimulates hepatitis B virus (HBV) DNA replication in hepatocellular carcinoma cell lines that are transiently or stably-transfected wit...

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Autors principals: Lin Yuan, Qianying Jia, Shenyong Yang, Nur Fazleen Binti Idris, Yimin Li, Yang Wang, Ya Zhao, Jieli Hu, Yuan Hu, Ailong Huang, Zeng Tu
Format: Artigo
Idioma:Inglês
Publicat: IMR Press 2020-01-01
Col·lecció:Frontiers in Bioscience-Landmark
Matèries:
adenosine deaminase
rna1
adar1
hepatitis b virus
rna editing
replication
Accés en línia:https://www.imrpress.com/journal/FBL/25/4/10.2741/4830
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