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The importance of antibody dependent cell-mediated cytotoxicity (ADCC) for breast cancer response to trastuzumab - Herceptin

In this work we investigated the direct or indirect (through ADCC) cytotoxic action of Herceptin, to two breast carcinoma cell lines: to MDA-MB 361, for HER-2, IHC score (3+) and to MDA-MB 453, IHC score (<2+). Cytotoxic action of Herceptin, of PBMC and of their combination (ADCC) was determi...

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Detalhes bibliográficos
Main Authors: Juranić Zorica D., Stanojević-Bakić Nevenka, Nešković-Konstantinović Zora, Žižak Željko, Stanojković Tatjana, Radulović Siniša S., Milošević Dušanka
Formato: Artigo
Idioma:Inglês
Publicado em: Institute of Oncology, Sremska Kamenica, Serbia 2002-01-01
Colecção:Archive of Oncology
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Acesso em linha:http://www.doiserbia.nb.rs/img/doi/0354-7310/2002/0354-73100203162J.pdf
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