Hydrogel Formulations Incorporating Drug Nanocrystals Enhance the Therapeutic Effect of Rebamipide in a Hamster Model for Oral Mucositis

A mouthwash formulation of rebamipide (REB) is commonly used to treat oral mucositis; however, this formulation does not provide sufficient treatment or prevention in cases of serious oral mucositis. To improve treatment, we attempted to design a hydrogel incorporating REB nanocrystals (R-NPs gel)....

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Detalhes bibliográficos
Main Authors: Noriaki Nagai, Ryotaro Seiriki, Saori Deguchi, Hiroko Otake, Noriko Hiramatsu, Hiroshi Sasaki, Naoki Yamamoto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-06-01
Colecção:Pharmaceutics
Assuntos:
rebamipide
nanocrystals
oral mucositis
hydrogel
endocytosis
Acesso em linha:https://www.mdpi.com/1999-4923/12/6/532
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