Altered cortical processing of sensory input in Huntington disease mouse models

Huntington disease (HD), a hereditary neurodegenerative disorder, manifests as progressively impaired movement and cognition. Although early abnormalities of neuronal activity in striatum are well established in HD models, there are fewer in vivo studies of the cortex. Here, we record local field po...

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Detalhes bibliográficos
Main Authors: Marja D. Sepers, James P. Mackay, Ellen Koch, Dongsheng Xiao, Majid H. Mohajerani, Allen W. Chan, Amy I. Smith-Dijak, Daniel Ramandi, Timothy H. Murphy, Lynn A. Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-07-01
Colecção:Neurobiology of Disease
Assuntos:
Cortex
Huntington disease
Mouse model
Electrophysiology
Mesoscopic imaging
In vivo
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996122001322
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