Mesenchymal stem cells from patients with chronic myeloid leukemia do not express BCR-ABL and have absence of chimerism after allogeneic bone marrow transplant

Bone marrow is a heterogeneous cell population which includes hematopoietic and mesenchymal progenitor cells. Dysregulated hematopoiesis occurs in chronic myelogenous leukemia (CML), being caused at least in part by abnormalities in the hematopoietic progenitors. However, the role of mesenchymal ste...

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Detalhes bibliográficos
Main Authors: R.C.V. Carrara, M.D. Orellana, A.M. Fontes, P.V.B. Palma, S. Kashima, M.R. Mendes, M.A. Coutinho, J.C. Voltarelli, D.T. Covas
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2007-01-01
Colecção:Brazilian Journal of Medical and Biological Research
Assuntos:
Mesenchymal stem cells
Chimerism
Allogeneic hematopoietic stem cell transplantation
Chronic myeloid leukemia
bcr-abl gene
Acesso em linha:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100008
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