Clinical Performance of Nanopore Targeted Sequencing for Diagnosing Infectious Diseases

ABSTRACT The gold standard for confirming bacterial infections is culture-positive, which has a long sample-to-result turnaround time and poor sensitivity for unculturable and fastidious pathogens; therefore, it is hard to guide early, targeted antimicrobial therapy and reduce overuse of broad-spect...

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Detalhes bibliográficos
Main Authors: Yu Fu, Qingsong Chen, Mengyuan Xiong, Jin Zhao, Shucheng Shen, Liangjun Chen, Yunbao Pan, Zhiqiang Li, Yirong Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-04-01
Colecção:Microbiology Spectrum
Assuntos:
clinical performance
infectious diseases
nanopore targeted sequencing
polymerase chain reaction
sanger sequencing
sensitivity
Acesso em linha:https://journals.asm.org/doi/10.1128/spectrum.00270-22
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