Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by chronic inflammation and airway remodeling. Human epididymis protein 4 (HE4) plays a critical role in various inflammatory or fibrotic diseases. However, the role of HE4 in COPD remains unident...

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Detalhes bibliográficos
Main Authors: Yuan Zhan, Jinkun Chen, Jixing Wu, Yiya Gu, Qian Huang, Zhesong Deng, Shanshan Chen, Xiaojie Wu, Yongman Lv, Zhilin Zeng, Jungang Xie
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Respiratory Research
Assuntos:
Human epididymis protein 4
Airway epithelium inflammation
Fibroblast differentiation and proliferation
Chronic obstructive pulmonary disease
Acesso em linha:https://doi.org/10.1186/s12931-022-02040-7
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