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Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation

Autophagy is an evolutionarily conserved self-protecting mechanism implicated in cellular homeostasis. ATG4B plays a vital role in autophagy process via undertaking priming and delipidation of LC3. Chemical inhibitors and regulative modifications such as oxidation of ATG4B have been demonstrated to...

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Detalhes bibliográficos
Main Authors: Fan Xia, Yuanyuan Fu, Huazhong Xie, Yuxin Chen, Dongmei Fang, Wei Zhang, Peiqing Liu, Min Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-06-01
Colecção:Redox Biology
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231722000568
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