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Duloxetine, a Balanced Serotonin-Norepinephrine Reuptake Inhibitor, Improves Painful Chemotherapy-Induced Peripheral Neuropathy by Inhibiting Activation of p38 MAPK and NF-κB

Chemotherapy-induced peripheral neuropathy (CIPN) is a severe, toxic side effect that frequently occurs in anticancer treatment and may result in discontinuation of treatment as well as a serious reduction in life quality. The CIPN incidence rate is as high as 85–90%. Unfortunately, there is current...

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Detalhes bibliográficos
Main Authors: Jing Meng, Qiuyan Zhang, Chao Yang, Lu Xiao, Zhenzhen Xue, Jing Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-04-01
Colecção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2019.00365/full
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