Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival

Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular classifications and histo‐molecular gradients have been proposed to describe heterogeneity, but a deeper understanding of gene mutations in the contex...

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Detalhes bibliográficos
Main Authors: Lisa Quetel, Clément Meiller, Jean‐Baptiste Assié, Yuna Blum, Sandrine Imbeaud, François Montagne, Robin Tranchant, Julien deWolf, Stefano Caruso, Marie‐Christine Copin, Véronique Hofman, Laure Gibault, Cécile Badoual, Ecaterina Pintilie, Paul Hofman, Isabelle Monnet, Arnaud Scherpereel, Françoise Le Pimpec‐Barthes, Jessica Zucman‐Rossi, Marie‐Claude Jaurand, Didier Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-06-01
Colecção:Molecular Oncology
Assuntos:
gene mutations
prognosis
thoracic cancer
tumor heterogeneity
tumor molecular classification
Acesso em linha:https://doi.org/10.1002/1878-0261.12651
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