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Mixed lineage leukaemia histone methylases 1 collaborate with ERα to regulate HOXA10 expression in AML

HOXA10, a homeobox-containing gene involved in definitive haematopoiesis, which implicated in the pathogenesis of AML (acute myeloid leukaemia), has been studied extensively. But the regulatory mechanism that drives HOXA10 expression is still unclear. In the present paper, HOXA10 regulated by MLL1 (...

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Detalhes bibliográficos
Main Authors: Jie Yao, Li‑Chao Fang, Zai‑Lin Yang, Hui Huang, Yan Li, Jun Deng, Junsong Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press, Biochemical Society 2014-12-01
Colecção:Bioscience Reports
Assuntos:
AML
Acesso em linha:http://www.bioscirep.org/bsr/034/e156/bsr034e156.htm
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