Increased production of IL-4 and IL-12p40 from bronchoalveolar lavage cells are biomarkers of Mycobacterium tuberculosis in the sputum.

Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sputum smear is a biomarker for contagiousness.We enro...

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Main Authors: Anna Nolan, Elaine Fajardo, Maryann L Huie, Rany Condos, Anil Pooran, Rodney Dawson, Keertan Dheda, Eric Bateman, William N Rom, Michael D Weiden
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3603887?pdf=render
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