Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth

Abstract Millions suffer from skin diseases. Functional interfollicular epidermal stem cells are needed in skin therapy or drug screening in vitro. We obtained functional interfollicular epidermal stem cells with intact stemness and cell junctions by treating them with Wnt3a. Moreover, epidermal ste...

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Detalhes bibliográficos
Main Authors: Ling Leng, Jie Ma, Luye Lv, Wenjuan Wang, Dunqin Gao, Yunping Zhu, Zhihong Wu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-09-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Epidermal stem cell
Extracellular vesicle
Organoids
Proteomics
Epidermal development
Extracellular matrix
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01933-y
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