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Using Integrative Analysis of DNA Methylation and Gene Expression Data in Multiple Tissue Types to Prioritize Candidate Genes for Drug Development in Obesity

Obesity has become a major public health issue which is caused by a combination of genetic and environmental factors. Genome-wide DNA methylation studies have identified that DNA methylation at Cytosine-phosphate-Guanine (CpG) sites are associated with obesity. However, subsequent functional validat...

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Detalhes bibliográficos
Main Authors: Qingjie Guo, Ruonan Zheng, Jiarui Huang, Meng He, Yuhan Wang, Zonghao Guo, Liankun Sun, Peng Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-12-01
Colecção:Frontiers in Genetics
Assuntos:
CpG
Acesso em linha:https://www.frontiersin.org/article/10.3389/fgene.2018.00663/full
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