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Correlation of chromosome damage and promoter methylation status of the DNA repair genes MGMT and hMLH1 in Chinese vinyl chloride monomer (VCM)-exposed workers
Objective: To explore the association of the methylation status of MGMT and hMLH1 with chromosome damage induced by vinyl chloride monomer (VCM). Materials and Methods: Methylation of MGMT and hMLH1 was measured in 101 VCM-exposed workers by methylation-specifi c PCR. Chromosome damage in peripheral...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nofer Institute of Occupational Medicine
2013-02-01
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| 叢編: | International Journal of Occupational Medicine and Environmental Health |
| 主題: | |
| 在線閱讀: | http://ijomeh.eu/Correlation-of-chromosome-damage-and-promoter-methylation-status-of-the-dna-repair-genes-mgmt-and-hmlh1-in-chinese-vinyl-chloride-monomer-vcm-exposed-workers,2225,0,2.html |
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