Rho-Associated Protein Kinase Inhibitor Treatment Promotes Proliferation and Phagocytosis in Trabecular Meshwork Cells

PurposeContinuous reductions in trabecular meshwork (TM) cellularity inhibit aqueous humor (AH) outflow, which is the main cause of primary open-angle glaucoma. Rho-associated protein kinase inhibitor (ROCKi) targets the TM to reduce intraocular pressure (IOP) and increase AH outflow facility. Howev...

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Autori principali: Wenshi Chen, Xuejiao Yang, Jingwang Fang, Yuqing Zhang, Wei Zhu, Xian Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-03-01
Serie:Frontiers in Pharmacology
Soggetti:
Rho-associated protein kinase inhibitor
glaucoma
trabecular meshwork
proliferation
phagocytosis
Accesso online:https://www.frontiersin.org/article/10.3389/fphar.2020.00302/full
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