Rho-Associated Protein Kinase Inhibitor Treatment Promotes Proliferation and Phagocytosis in Trabecular Meshwork Cells

PurposeContinuous reductions in trabecular meshwork (TM) cellularity inhibit aqueous humor (AH) outflow, which is the main cause of primary open-angle glaucoma. Rho-associated protein kinase inhibitor (ROCKi) targets the TM to reduce intraocular pressure (IOP) and increase AH outflow facility. Howev...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wenshi Chen, Xuejiao Yang, Jingwang Fang, Yuqing Zhang, Wei Zhu, Xian Yang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020-03-01
Cyfres:Frontiers in Pharmacology
Pynciau:
Rho-associated protein kinase inhibitor
glaucoma
trabecular meshwork
proliferation
phagocytosis
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fphar.2020.00302/full
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