Rho-Associated Protein Kinase Inhibitor Treatment Promotes Proliferation and Phagocytosis in Trabecular Meshwork Cells

PurposeContinuous reductions in trabecular meshwork (TM) cellularity inhibit aqueous humor (AH) outflow, which is the main cause of primary open-angle glaucoma. Rho-associated protein kinase inhibitor (ROCKi) targets the TM to reduce intraocular pressure (IOP) and increase AH outflow facility. Howev...

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Bibliographic Details
Main Authors: Wenshi Chen, Xuejiao Yang, Jingwang Fang, Yuqing Zhang, Wei Zhu, Xian Yang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
Rho-associated protein kinase inhibitor
glaucoma
trabecular meshwork
proliferation
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00302/full
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