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Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway

Summary: Normally, opioids function in a receptor-dependent manner. They bind to opioid receptors, activate or inhibit receptor activation, and subsequently modulate downstream signal transduction. However, the complex functions of opioids and the low expression of opioid receptors and their endogen...

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Main Authors: Lining Liang, Jinlong Chen, Yuan Li, Xiaowei Lai, Hao Sun, Changpeng Li, Mengdan Zhang, Tingting Yang, Fei Meng, Ping-Yee Law, Horace H. Loh, Hui Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-03-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124720302448
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