A Three-Genes Signature Predicting Colorectal Cancer Relapse Reveals LEMD1 Promoting CRC Cells Migration by RhoA/ROCK1 Signaling Pathway

ObjectiveColorectal cancer (CRC) patients that experience early relapse consistently exhibit poor survival. However, no effective approach has been developed for the diagnosis and prognosis prediction of postoperative relapsed CRC.MethodsMultiple datasets from the GEO database and TCGA database were...

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Detalhes bibliográficos
Main Authors: Hui Zhang, Chenxin Xu, Feng Jiang, Jifeng Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Oncology
Assuntos:
LEMD1
relapse model
RhoA
EMT
colorectal cancer
metastasis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.823696/full
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