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Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis.

In mammals, germ cells within the developing gonad follow a sexually dimorphic pathway. Germ cells in the murine ovary enter meiotic prophase during embryogenesis, whereas germ cells in the embryonic testis arrest in G0 of mitotic cell cycle and do not enter meiosis until after birth. In mice, retin...

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Detalhes bibliográficos
Main Authors: Hui Li, Glenn MacLean, Don Cameron, Margaret Clagett-Dame, Martin Petkovich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-10-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2760134?pdf=render
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