WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish

ABSTRACT Granulomas are the pathological hallmark of tuberculosis (TB). In individuals with latent TB infection, Mycobacterium tuberculosis cells reside within granulomas in a nonreplicating dormant state, and a portion of them will develop active TB. Little is known on the bacterial mechanisms/fact...

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Bibliographische Detailangaben
Hauptverfasser: Chen Lin, Yuting Tang, Yuchen Wang, Junli Zhang, Yeyu Li, Shuqin Xu, Bin Xia, Qiran Zhai, Yao Li, Lu Zhang, Jun Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2022-04-01
Schriftenreihe:Microbiology Spectrum
Schlagworte:
WhiB4
latency
reactivation
tuberculosis
zebrafish
Online Zugang:https://journals.asm.org/doi/10.1128/spectrum.00443-21
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