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Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.
Two phenylalanines (FF) in an acidic tract (FFAT)-motifs were originally described as having seven elements: an acidic flanking region followed by 6 residues (EFFDA-E). Such motifs are found in several lipid transfer protein (LTP) families, and they interact with a protein on the cytosolic face of t...
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Main Authors: | , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Public Library of Science (PLoS)
2012-01-01
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叢編: | PLoS ONE |
在線閱讀: | http://europepmc.org/articles/PMC3261905?pdf=render |
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