Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.

The lungs are a noted predilection site of acute, latent, and reactivated cytomegalovirus (CMV) infections. Interstitial pneumonia is the most dreaded manifestation of CMV disease in the immunocompromised host, whereas in the immunocompetent host lung-infiltrating CD8 T cells confine the infection i...

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Hauptverfasser: Stefan Ebert, Marc Becker, Niels A W Lemmermann, Julia K Büttner, Anastasija Michel, Christian Taube, Jürgen Podlech, Verena Böhm, Kirsten Freitag, Doris Thomas, Rafaela Holtappels, Matthias J Reddehase, Michael Stassen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2014-04-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC3999167?pdf=render
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