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Up-regulated expression of E2F2 is necessary for p16INK4a-induced cartilage injury

Abstract Background Cartilage degradation would result in osteoarthritis (OA). p16INK4awas found in some age-related diseases. In this study, we aimed to determine the role of p16INK4a during OA and to investigate the underlying mechanisms. Methods Enzyme-linked immunosorbent assay (ELISA) was perfo...

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Detalles Bibliográficos
Main Authors: Xinnan Bao, Xinyu Hu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-09-01
Series:BMC Musculoskeletal Disorders
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Acceso en liña:http://link.springer.com/article/10.1186/s12891-018-2253-x
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