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Up-regulated expression of E2F2 is necessary for p16INK4a-induced cartilage injury
Abstract Background Cartilage degradation would result in osteoarthritis (OA). p16INK4awas found in some age-related diseases. In this study, we aimed to determine the role of p16INK4a during OA and to investigate the underlying mechanisms. Methods Enzyme-linked immunosorbent assay (ELISA) was perfo...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
BMC
2018-09-01
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Series: | BMC Musculoskeletal Disorders |
Assuntos: | |
Acceso en liña: | http://link.springer.com/article/10.1186/s12891-018-2253-x |
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