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Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.
In contrast to Trypanosoma brucei gambiense and T. b. rhodesiense (the causative agents of human African trypanosomiasis), T. b. brucei is lysed by apolipoprotein-L1 (apoL1)-containing human serum trypanolytic factors (TLF), rendering it non-infectious to humans. While the mechanisms of TLF1 uptake,...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2018-01-01
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| Schriftenreihe: | PLoS Pathogens |
| Online Zugang: | http://europepmc.org/articles/PMC5790291?pdf=render |
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