lncRNA PRADX is a Mesenchymal Glioblastoma Biomarker for Cellular Metabolism Targeted Therapy

Glioblastoma (GBM) is the most common and lethal type of primary malignant central nervous system (CNS) tumor with an extremely poor prognosis, and the mesenchymal subtype of GBM has the worst prognosis. Here, we found that lncRNA PRADX was overexpressed in the mesenchymal GBM and was transcriptiona...

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Detalhes bibliográficos
Main Authors: Can Xu, Jixing Zhao, Jia Song, Menglin Xiao, Xiaoteng Cui, Lei Xin, Jianglong Xu, Yuhao Zhang, Kaikai Yi, Biao Hong, Fei Tong, Shaohui Tian, Yanli Tan, Chunsheng Kang, Chuan Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Oncology
Assuntos:
mesenchymal GBM
lncRNA
RUNX1-CBFβ complex
STAT3 pathway
energy metabolism
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.888922/full
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