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Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells

<p>Abstract</p> <p>Background</p> <p>Norrin is a potent Wnt pathway ligand. Aberrant activation of this signaling pathway can result in colon tumors but the role of norrin-based signaling in the genesis of colon cancer, and its relationship to activation of the pathway...

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Autori principali: Pérez Cherlyn A, Nguyen Anthony V, Moyer Mary, Planutiene Marina, Planutis Kestutis, Holcombe Randall F
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2007-03-01
Serie:BMC Cell Biology
Accesso online:http://www.biomedcentral.com/1471-2121/8/12
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