Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli.

Disulfide-rich peptides are the dominant component of most animal venoms. These peptides have received much attention as leads for the development of novel therapeutic agents and bioinsecticides because they target a wide range of neuronal receptors and ion channels with a high degree of potency and...

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Main Authors: Julie K Klint, Sebastian Senff, Natalie J Saez, Radha Seshadri, Ho Yee Lau, Niraj S Bende, Eivind A B Undheim, Lachlan D Rash, Mehdi Mobli, Glenn F King
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3646780?pdf=render
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