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Exosomal miR-223 derived from natural killer cells inhibits hepatic stellate cell activation by suppressing autophagy
Abstract Background Activation of hepatic stellate cells (HSCs) is a prominent driver of liver fibrosis. We previously demonstrated that exosomes derived from natural killer (NK) cells (NK-Exo) attenuated TGF-β1-induced HSC activation. Herein, this study was designed to investigate the mechanism und...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-09-01
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| Colecção: | Molecular Medicine |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s10020-020-00207-w |
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