USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

Abstract Background The deubiquitinating (DUB) enzyme ubiquitin-specific protease 18 (USP18), also known as UBP43, is an ubiquitin-specific protease linked to several human malignancies. However, USP18’s underlying function in human cervical cancer remains unclear. In the current study, we aimed to...

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Hauptverfasser: Wenjing Diao, Qisang Guo, Caiying Zhu, Yu Song, Hua Feng, Yuankui Cao, Ming Du, Huifen Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-08-01
Schriftenreihe:BMC Cancer
Schlagworte:
Cervical cancer
USP18
AKT
Proliferation
Apoptosis
Online Zugang:http://link.springer.com/article/10.1186/s12885-020-07241-1
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